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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
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Your Position :Home->Past Journals Catalog->2005 Vol.24 No.1

Anesthesia Technic and Perioperative Management in Pigs with Pancreatic-duodenal Transplantation
Author of the article:YAO Jun-yan, WANG Quan-yun, WEI Xin-chuan
Author's Workplace:(Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041)
Key Words:pig; pancreatic-duodenal transplantation; anesthesia; perioperative margement
Abstract:Objective To establish the model of pancreatic-duodenal transplantation with portal-enteric drainage in pigs and to investigate anesthesia technic and perioperative management of the procedure. Methods Forty pigs were matched according to the weight and assigned randomly to the donor and recipient groups. After basic anesthesia, the animals were induced with thiopental sodium and intubation was facilitated with succinylcholine. Then mechanical ventilation was applie, and the anesthesia was maintained with the combination of midazolam, fentanyl, pipecuronium and thiopental intravenously. The right internal carotid artery was cannulated in order to monitor the mean artery pressure, the heart rate, SpO2 and the central venous pressure simultaneously. The blood samples from right jugular vein were collected for analyzing the concentration of blood sugar, insulin and glucagon. Results The model was set up successfully and the intubation was improved with the successful rate of 95%. Conclusion The anesthesia was performed easily and securely. Proper volume therapy during the apancreatic stage could maintain hemodynamic and respiratory stabilization after infusion of the graf.
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