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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
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Your Position :Home->Past Journals Catalog->2008 Vol.27 No.5

Effect of Corticosterone on Ornithine Decarboxylase and Antizyme Gene Expression in Rat Regenerating Liver
Author of the article:SUO Shi-ying1, CAO Lan-ju2, MA Jian-min1, NING Qian-ji
Author's Workplace:(1. College of Life Science, Henan Normal University, Xinxiang , Henan Province 453007, China; 2. College of Physical Education, Henan Normal University)
Key Words:corticosterone; ornithine decarboxylase; antizyme; regenerating liver
Abstract:The male SD rats (180~200 g) were used to investigate the effect of corticosterone on ornithine decarboxylase (ODC) and antizyme mRNA levels in early regenerating liver induced by partial hepatectomy with RT-PCR. Results indicated that corticosterone inhibited dose-dependently the level of ODC mRNA. The effects of 10 mg/kg and 20 mg/kg body weight corticosterone on antizyme mRNA expression were not obvious, however, 40 mg/kg corticosterone treatment could stimulate antizyme gene transcription.
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